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5–four μmol/L range,[156][157] the focus of serotonin in synaptic vesicles was measured at 270 mM.[182] pursuing vesicular release, the resulting concentration of serotonin in the synaptic cleft, to which serotonin receptors are exposed, is believed to become about 300 μmol/L. Hence, whilst in vitro receptor binding affinities, efficacies, an
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